- Ireland, John (English composer)
- Ireland, John (South African pop)
- Ireland, Jordie
- Ireland, Mike and Holler
- İrem (Turkish pop)
- İrem, İlhan
- Irena (Polish band)
- Irencros
- Irene (Swedish band)
- Irene (aka Irene Stelmakovich)
- Irenegarry (Spanish singer-songwriter)
- Irepelusa
- Iress
- Irfan, Mohammed
- Irgens, Henrik (Danish multi-instrumentalist)
- Irglová, Markéta
- Irglová, Markéta and Hansard, Glen
- iri (Female vocalist/rapper)
- Iridium (Louisiana Rock Band)
- Iridium (Metal-Core band from Colorado, USA)
- Irie FM (Reggae band from Belgrade)
- Irie Love
- Irie Maffia
- Irie Maffia feat. Beenie Man
- Irie Révoltés
- Irie Souljah
- Irie, Evie (Australian Pop Singer)
- Irie, Jun (composer and arranger)
- Irie, The (Reggae/Alt Band from Arizona)
- Irie, Tippa
- Iriepathie
- Iriepathie feat. Irie Révoltés
- Iriepathie feat. Zos & Kaa, Uwe
- Irigy Hónaljmirigy
- Irina (Finnish singer Irina Saari)
- Iriondo, Silvia (Argentine ethnomusicologist, composer and singer)
- Iris (Texan synthpop band)
- IRIS (Romanian rock band)
- Iris (A pop / rock british group)
- Iris (Belgian Singer Laura van den Bruel)
- iRis (Idol group)
- IRIS (Portuguese Rock band)
- Iris (Australia)
- iris (Norwegian singer-songwriter)
- Iris (Montreal-based pop singer/drummer)
- Iris (shoegaze band from Toronto, Canada)
- Iris (Swedish psychedelic/progressive rock group)
- Iris & Rose: "Wild & Thorny"
- iris & SKAAR
- Iris Bevy
- Iris Doe (Project from Jeffrey Cain of The Church)
- Iris, Donnie
- Irisa
- Irish All-Stars
- Irish Brigade, The (Irish Rebel Band from Co. Tyrone (Northern Ireland))
- Irish Coffee (Belgian hard rock band)
- Irish Descendants, The
- Irish Drovers
- Irish Front, The (Death metal band)
- Irish Handcuffs
- Irish Moutarde
- Irish Mythen
- Irish Rovers, The (Irish Canadian folk rock aka The Rovers)
- Irish Stew of Sindidun
- Irish Tenors, The
- Irish Women in Harmony
- Irist
- Irko (French rapper)
- Irl Sam
- Irma (Swedish pop singer)
- Irma (Cameroun/French singer)
- Irma Thomas & the Professionals (New Orleans Blues)
- Irma y Oswado
- Irmak, Sinem
- Irmão Victor
- Irmãos Catita
- Irmãos Verdades
- Irminsul
- Iro (Brooklyn, NY, United States)
- Irodorimidori
- IROH (Russian rapper)
- iroha (English rock band, bassist from Jesu)
- IRON
- Iron & Wine
- Iron & Wine & Bridwell, Ben
- Iron & Wine and Calexico
- Iron Age
- Iron Angel
- Iron Bell Music
- Iron Butterfly