- Isolated Youth
- Isolation Berlin
- Isolation Years
- Isolation, In
- Isole
- Isolée
- Isomer, Sin
- Isometry
- isomonstrosity
- ISON (Cosmic drone from Sweden)
- Ison & Fille
- Ison & Fille feat. Amin
- Ison & Fille feat. Amin & Sseruwagi, Mogge
- Ison & Fille feat. Fre & Sseruwagi, Mogge
- Ison & Fille feat. Highwon
- Ison & Fille feat. Meles, Nebay & Rosh
- Ison & Fille feat. Zarate, Michelle
- IsOokSchitterend
- Isoscope
- Isosine
- Isostatic (ambient project aka Sean Costello)
- Isotalo, Suvi
- Isotope
- Isotope Soap
- Isotopes (Sydney, Aus. Melodic Hardcore)
- Isoul8
- Isović, Safet (Bosnian Folk singer)
- ISOxo (San Diego producer/dj)
- ISOxo & Ninajirachi
- ISOxo & Wavedash
- Ispolins
- Israel (1990s US Christian pop)
- Israel (probably australian hiphop)
- Israel & New Breed
- Israel & New Breed feat. Adams, Yolanda
- Israel & New Breed feat. Cristabel "Chica" Clack
- Israel & New Breed feat. McReynolds, Jonathan
- Israel & New Breed feat. Neal, Charlin
- Israel & New Breed feat. Putnam, BJ
- Israel & New Breed feat. T-Bone
- Israel & Rodolffo
- Israel & Rodolffo & Castela, Ana
- Israel & Rodolffo & Jorge & Mateus
- Israel & Rodolffo & Juliette
- Israel & Rodolffo & Kevinho
- Israel & Rodolffo & Mari Fernandez
- Israel & Rodolffo part. Araújo, Cristiano
- Israel & Rodolffo part. Humberto & Ronaldo
- Israel & Rodolffo part. Jorge & Mateus
- Israel & Rodolffo part. Lima, Gusttavo
- Israel & Rodolffo part. Matheus & Kauan
- Israel B
- Israel B & Lowlight
- Israel Fernández
- Israel Fernández y Diego del Morao
- Israel Novaes
- Israel Philharmonic Orchestra (Israeli orchestra)
- Israel Vibration
- Israel, Dan
- Israel, Haim
- Israel, Jake
- Israel, Joseph
- Israel's Arcade
- Israelites, The (USA Christian Ska)
- Israelsson, Karl-Erik
- Issa (Norwegian Singer)
- Issa Gold (The Underachievers)
- Issa, Sámer
- Issaba (Rappeur fr)
- Issac, Barry
- Issam (Moroccan rapper)
- Isserley (witch house)
- Issey Cross
- ISSUE (US rap artist)
- Issues
- Issues feat. Langston, Jon
- Issues feat. Nylo
- ist
- IST IST (Manchester post-punk group)
- Istanbul Oriental Ensemble
- İstanbul Trip
- Istapp (Swedish melodic black metal)
- Istasha
- Isten Háta Mögött
- Istentales
- Isterband
- Istomin, Eugene, Rose, Leonard, Stern, Isaac
- Istoria (Istoria Band from Malaysia)
- Istrefi, Era
- István, Tabáni